Kevin Mills, Assistant Professor
Kevin Mills, Ph.D., and his laboratory team are immersed in research that is revealing new details about DNA break and repair mechanisms. Insights from their research could contribute to new therapies for cancer and other diseases.
Mills and his team are exploring the mechanisms that maintain genome stability, including the two predominant DNA repair pathways, and how they relate to human pathology. Another goal is to clarify the mechanisms of chromosomal translocations, where genetic material is exchanged between chromosomes. Certain translocations can lead to the development of cancer, and Mills is examining how nuclear architecture, genome structure and DNA repair mechanisms all influence this process. The Mills laboratory is also investigating the connection between DNA damage and natural variations in aging, using the mouse as a model system to explore how genome stability control changes with age.
A molecular biologist who studies fundamental cancer processes, Mills joined The Jackson Laboratory’s scientific staff in 2005. That appointment came after Mills completed a five-year postdoctoral fellowship at the Children's Hospital of Harvard Medical School. He received his B.A. in molecular biology, with a minor in biochemistry, from the University of Colorado, Boulder in 1994, and he completed his Ph.D. in biology at the Massachusetts Institute of Technology in 1999.